Sequential administration of interferon γ and interleukin-2 in metastatic renal cell carcinoma: results of a phase II trial
✍ Scribed by Manuela Schmidinger; Günther G. Steger; Catharina Wenzel; Gottfried J. Locker; Thomas Brodowicz; Alexandra C. Budinsky; Christoph Wiltschke; Gero Kramer; Michael Marberger; Christoph C. Zielinski; for the Austrian Renal Cell Carcinoma Study Group
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 111 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0340-7004
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## RESULTS. Fifty-five patients were enrolled in the trial and 52 were evaluable for ogy, The University of Texas M. D. Anderson response. All patients experienced fever and flu-like symptoms. Grade 3 or 4 nonhe-Cancer Center, Houston, Texas. matologic toxic effects included hypertension (48%), d
## Abstract ## BACKGROUND The objective of this study was to determine the response rate and toxicity of gemcitabine and continuous‐infusion 5‐fluorouracil (5‐FU) in combination with subcutaneous interleukin‐2 (IL2) and interferon‐α (IFNA) in patients with metastatic renal cell carcinoma. ## METH