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Sequential activation of protein kinase C δ and JNK is required for interferon-α-induced expression of IFIT4

✍ Scribed by Xiangyang Huang; Nanping Yang; Xuemei Ou; Dong Li; Zhongming Wang; Qibing Xie; Yongtao Chen; Hui Lin; Gen Yin; Fuqiang Wen

Book ID
113528136
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
812 KB
Volume
20
Category
Article
ISSN
0898-6568

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## Abstract **Background:** Cell lines that stably over‐express protein kinase C (PKC) δ frequently show a decrease in growth rate and saturation density, leading to the hypothesis that PKCδ has a negative effect on cell proliferation. However, the mode of PKCδ activation, the cell cycle stage requ