Sequencing of four new BoLA-DRB3 and six new BoLA-DQB alleles
β Scribed by J.-C. Maillard; I. Chantal; D. Berthier
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 92 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0268-9146
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## Summary Bovine MHC (__BoLA__β) __DRB3__ alleles encoded by the __DH8A__, __DH22A__ and __DH24A__ class II haplotypes were cloned from cDNA and characterized by sequence analysis. Comparison with other fullβlength __DRB3__ sequences suggested that __DRB3__ alleles may have evolved through multipl
Potential associations were investigated between bovine leucocyte antigen (BoLA) alleles and occurrence of disease. Cows (Holstein n = 835; Jersey n = 66) were examined for polymorphisms of the second exon of the BoLA-DRB3 gene, using the polymerase chain reaction (PCR), followed by digestion of the