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Sequences and evolution of mammalianRHgene transcripts and proteins

✍ Scribed by P.-A. Apoil; A. Blancher


Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
376 KB
Volume
49
Category
Article
ISSN
0093-7711

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Neutral Evolution of Model Proteins: Dif
✍ Ugo Bastolla; H.Eduardo Roman; Michele Vendruscolo πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 244 KB

We stimulate the evolution of model protein sequences subject to mutations. A mutation is considered neutral if it conserves (1) the structure of the ground state, (2) its thermodynamic stability and (3) its kinetic accessibility. All other mutations are considered lethal and are rejected. We adopt