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Evolution of sequences within protein superfamilies

โœ Scribed by M. O. Dayhoff; P. J. McLaughlin; W. C. Barker; L. T. Hunt

Publisher
Springer
Year
1975
Tongue
English
Weight
981 KB
Volume
62
Category
Article
ISSN
0028-1042

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The EF-hand motif, which assumes a helix-loop-helix structure normally responsible for Ca 2ฯฉ binding, is found in a large number of functionally diverse Ca 2ฯฉ binding proteins collectively known as the EF-hand protein superfamily. In many superfamily members, Ca 2ฯฉ binding induces a conformational c