✦ LIBER ✦

Sequence variation in the hypervariable region 1 of hepatitis C virus and posttransplantation recurrent hepatitis

✍ Scribed by Enrico Silini; Luca Belli; Sabrina Brambilla; Luciana Foti; Chiara Gritti; Antonella Lisa; Alberto Battista Alberti; Marilina Vinci; Luciano De Carlis; Gianfranco Rondinara; Giovanbattista Pinzello

Book ID: 111723436
Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 94 KB
Volume: 9
Category: Article
ISSN: 1527-6465
DOI: 10.1053/jlts.2003.50180

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Rapid sequence variation of the hypervar

Rapid sequence variation of the hypervariable region of hepatitis C virus during the course of chronic infection

✍ Masayuki Kurosaki; Nobuyuki Enomoto; Fumiaki Marumo; Chifumi Sato 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 798 KB

To evaluate the clinical significance of sequence variations in the hypervariable region of hepatitis C virus during the course of chronic infection, we performed pairwise comparison of the predominant nucleotide sequences. Hepatitis C virus RNA was extracted from two plasma samples obtained from 12

Antibody responses to hepatitis C virus

Antibody responses to hepatitis C virus hypervariable region 1: Evidence for cross-reactivity and immune-mediated sequence variation

✍ Mario U. Mondelli; Antonella Cerino; Antonella Lisa; Sabrina Brambilla; Laura Se 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

## Sequence heterogeneity of hepatitis C virus (HCV) is unevenly distributed along the genome, and maximal variation is confined to a short sequence of the HCV second envelope glycoprotein (E2), designated hypervariable region 1 (HVR1), whose biological function is still undefined. We prospectivel

Hypervariable region sequence in cryoglo

Hypervariable region sequence in cryoglobulin-associated hepatitis C virus in sera of patients with chronic hepatitis C: Relationship to antibody response against hypervariable region genom

✍ T Aiyama; K Yoshioka; A Okumura; M Takayanagi; K Iwata; T Ishikawa; S Kakumu 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB 👁 2 views

Nucleotide sequence variation in the hyp

Nucleotide sequence variation in the hypervariable region of the hepatitis C virus in the sera of chronic hepatitis C patients undergoing controlled interferon-α therapy

✍ Yeh, Byung-Il; Han, Kwang-Hyub; Oh, Seung-Hee; Kim, Hyon-Suk; Hong, Suk-Hyun; Oh 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 822 KB

Ten patients with hepatitis C virus (HCV) infection (experimental group) were treated with interferon-a (IF-a). Dosage was six million units per day for one week and then three times a week for another six months. Seven HCV-infected patients (control group) did not receive IF-a therapy. The hypervar

Variation in the hepatitis C virus NS5a

Variation in the hepatitis C virus NS5a region in relation to hypervariable region 1 heterogeneity during interferon treatment

✍ Odeberg, Jacob; Yun, Zhibing; Sönnerborg, Anders; Weiland, Ola; Lundeberg, Joaki 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 1 views

The putative interferon sensitivity determining region (ISDR) in the NS5a region of the hepatitis C virus (HCV) was analyzed in 13 interferon alpha (IFN-␣) treated patients representing genotypes 1a, 1b, and 2b. These patients had previously been followed longitudinally during treatment with respect

Sequence evolution and cross-reactive an

Sequence evolution and cross-reactive antibody responses to hypervariable region 1 in acute hepatitis C virus infection

✍ Sandra Hjalmarsson; Jonas Blomberg; Lena Grillner; Rüdiger Pipkorn; Tobias Allan 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB 👁 1 views

## Abstract Hepatitis C virus (HCV) infection may result in acute resolving or chronic infection. Patients that clear the infection have a more vigorous cellular immune response and an early humoral response to the hypervariable region 1 (HVR1) of the E2 envelope protein. To analyse further the pro