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Sequence to array: Probing the genome's secrets

✍ Scribed by Blanchard, Alan P.; Hood, Leroy


Book ID
109910876
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
145 KB
Volume
14
Category
Article
ISSN
1087-0156

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Automated fluorescent sequencers have now generated full and partial sequences of several eukaryotic genomes. How can we best use this information to discover new drugs? One important tool is mRNA expression profiling with DNA arrays. Large-scale high-density DNA arrays can be created for hybridizat