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Sequence of the —530 region of the β-globin gene of sickle cell anemia patients with the Arabian haplotype

✍ Scribed by Fan-yi Zeng; Griffin P. Rodgers; Shu-zhen Huang; Alan N. Schechter; Mohammad Salamah; Susan Perrine; Patricia E. Berg

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
330 KB
Volume
3
Category
Article
ISSN
1059-7794

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✦ Synopsis

Sickle cell anemia is caused by a mutation in the sixth codon of the p-globin gene. There is a vast range of severity in this disease, even among ps gene homozygotes . Five different haplotypes associated with the ps gene have been described, four in Africa (Bantu, Benin, Senegel, and Cameroon) and one found in both India and Saudi Arabia (IndiadArabian) (Chelbourne et al.,

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