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Sequence-Dependent Dynamics of Duplex DNA: The Applicability of a Dinucleotide Model

โœ Scribed by Okonogi, T.M.; Alley, S.C.; Reese, A.W.; Hopkins, P.B.; Robinson, B.H.


Book ID
118514828
Publisher
Biophysical Society
Year
2002
Tongue
English
Weight
185 KB
Volume
83
Category
Article
ISSN
0006-3495

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Melting experiments were conducted on 22 DNA dumbbells as a function of solvent ionic strength from 25-115 mM Na ฯฉ . The dumbbell molecules have short duplex regions comprised of 16 -20 base pairs linked on both ends by T 4 single-strand loops. Only the 4 -8 central base pairs of the dumbbell stems