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Sequence and localization of the gene encoding yeast phosphoglycerate mutase

✍ Scribed by Jürgen Heinisch; Robert C. Borstel; Rosaura Rodicio

Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
614 KB
Volume
20
Category
Article
ISSN
0172-8083

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✦ Synopsis

In this study we report on the complete nucleotide sequence of the yeast phosphoglycerate mutase gene (GPM1) and its essential 5' and 3' non-coding regions. The transcriptional start points were determined by S1-mapping and sequencing of a cDNA clone. Several sequences identified as important for transcriptional regulation in yeast promoters are present upstream of the transcription start point. 3' to the coding region we sequenced a composite repetitive element which, apparently, originated from a recombination between a delta- and a tau-element. Finally, we mapped the GPM1 gene 13 cM distal to fas1 on chromosome XI.

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