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Sequence analysis of the proximal promoter region of the human α-fetoprotein gene in hepatocellular carcinoma

✍ Scribed by Igarashi, Kentarou; Aoyagi, Yutaka; Ohkoshi, Showgo; Yokota, Tsuyoshi; Mori, Shigeki; Suda, Tsuyoshi; Kamimura, Tomoteru; Asakura, Hitoshi


Book ID
125438929
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
694 KB
Volume
76
Category
Article
ISSN
0304-3835

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For an approach of gene therapy for hepatocellular carcinoma (HCC), transcriptional regulatory sequence (TRS) of either alpha-fetoprotein (AFP) or albumin has been used for targeting cancer cells. To examine the feasibility of using TRSs of these genes for possible gene therapy of HCCs, the cellular