Sequence analysis of microgram amounts of peptides by mass spectrometry
β Scribed by John Lenard; Paul M. Gallop
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- English
- Weight
- 250 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0003-2697
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We report the application of nanoelectrospray ionization tandem mass spectrometry (nES-MS/MS) and capillary LC/microelectrospray MS/MS (cLC/&mgrES-MS/MS) for sequencing sulfonic acid derivatized tryptic peptides. These derivatives were specifically prepared to facilitate low-energy charge-site-initi
The analysis of peptide derivatives by fast atom bombardment, liquid secondary-ionization mass spectrometry, plasma desorption, electrospray ionization, and matrix-assisted laser desorption/ionization is reviewed. The fragmentation patterns of peptides and of charge-derivatized peptides are compared