A method for the separation of lidocaine and six of its metabolites in plasma has been developed. Separation was performed using a buffer consisting of Ε½ . 35 mM phosphaterTris pH 3.0, 6 mM cetyltrimetylammoniumbromid CTAB and Ε½ . 9% vrv methanol. The key variables, CTAB and methanol concentrations,
Separation of lidocaine and its metabolites by capillary electrophoresis using volatile aqueous and nonaqueous electrolyte systems
β Scribed by Zhi Wang; Hong Wan; Magnus S. Anderson; Mohamed Abdel-Rehim; Lars G. Blomberg
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 153 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0173-0835
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π SIMILAR VOLUMES
Buffer: 50 mM ammonium acetate-13.75 mM ammonia in water (1) or in methanol (2). Voltage: Γ25 kV in (1) and 25 kV in (2). Temperature: 25Β°C; wavelength: 280 nm; capillary: uncoated fused capillary (44 cm; 50 mm i.d.).
## Separation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using nonaqueous electrolytes The aim of the present work was to investigate the separation of nonsteroidal antiinflammatory drugs (NSAIDs: niflumic acid, flufenamic acid, piroxicam, alclofenac, tiaprofenic acid, fl