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Separation of complement-dependent and lymphocytedependent cytotoxic activity in human sera

✍ Scribed by June L. Miller; D. L. Mann; I. Yust

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
335 KB
Volume
5
Category
Article
ISSN
0014-2980

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✦ Synopsis

Abstract

Two human sera having both complement‐dependent and lymphocyte‐dependent antibody activities (CDA, LDA) were applied to isoelectrofocusing columns. Maximum LDA activity for both sera was found focused at a higher pH than maximum CDA activity. The studies suggest that LDA molecules may exist without having complement‐dependent activity.

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