Direct and complement dependent cytotoxi
✍
Clive S. Zent; Charla R. Secreto; Betsy R. LaPlant; Nancy D. Bone; Timothy G. Ca
📂
Article
📅
2008
🏛
Elsevier Science
🌐
English
⚖ 373 KB
The mechanism of cytotoxicity of alemtuzumab and rituximab in chronic lymphocytic leukemia (CLL) is not well understood. We obtained fresh CLL cells from early-intermediate stage high-risk patients just prior to treatment with alemtuzumab and rituximab to study mechanisms of action and resistance. A