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Separation of amino acid enentiomers by adding a chiral complex to the eluent

✍ Scribed by P. Masia; I. Nicoletti; M. Sinibaldi; D. Attanasio; A. Messina

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
392 KB
Volume
204
Category
Article
ISSN
0003-2670

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✦ Synopsis

Amino acid enantiomers are separated by reverse-phase chromatography with an optically active polyamine/Cu (II) complex in the mobile phase. The polyamine was obtained by reaction of ( -) -trans-1,2-diaminocyclohexane with ethylene glycol diglycidyl ether; the complex with copper (II) ions was used in the eluent. Separation factors are reported for ten amino acids and four barbiturates.

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