Separation and determination of pesticides by capillary electrophoresis. I. Rapid separation of fifteen N-methylcarbamate insecticides via micellar electrokinetic chromatography

✍ Scribed by Y.S. Wu; H.K. Lee; S.F.Y. Li

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 191 KB
• Volume: 10
• Category: Article
• ISSN: 1040-7685
• DOI: 10.1002/(sici)1520-667x(1998)10:3<239::aid-mcs1>3.0.co;2-h

✦ Synopsis

In this article, micellar electrokinetic chromatography MEKC separation of 15 N-methylcarbamate insecticides with a wide span of hydrophobicity was studied. Influences of various buffer parameters such as sodium dodecyl sulfate Ž . Ž . SDS concentration, ionic strength, and modifiers urea, cyclodextrins on separation selectivity and analysis time were investigated. Under the optimized running Ž condition 40 mM phosphate with 60 mM SDS and 23 mM hydroxypropyl-␤-cyclo-. dextrin, pH 7, voltage 18 kV , satisfactory separation of all 15 analytes was achieved in less than 14 min. Using this new method, residues of carbaryl and its metabolite in a paddy water sample were successfully determined. This new alternative for the separation of N-methylcarbamates is superior to conventional Ž . reversed-phase high-performance liquid chromatography HPLC approaches in terms of speed of separation and flexibility of selectivity manipulation.