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Separate mechanisms for placebo and opiate analgesia?

โœ Scribed by T.D. Wager; Mathieu Roy


Book ID
113839269
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
83 KB
Volume
150
Category
Article
ISSN
0304-3959

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Two double blind cross-over studies were performed using a submaximal effort tourniquet test (SETT) in healthy volunteers to investigate the role of endogenous opioids in placebo analgesia. In the first study IV naloxone significantly inhibited analgesia, miosis and sedation produced by the opioid d