## BACKGROUND. Sentinel lymph node biopsy following radioisotope labeling is a recently developed, minimally invasive surgical staging procedure used in the management of primary cutaneous malignant melanoma. If histologic analysis reveals melanoma metastasis in the sentinel lymph node, completion
Sentinel lymph node in melanoma: use of molecular biology (RT-PCR) in the detection of occult metastases
โ Scribed by L. Riccioni; P. Farabegoli; O. Nanni; F. Morigi; M. Polverelli; G. Landi; F. Giangaspero
- Publisher
- Springer
- Year
- 2002
- Tongue
- Italian
- Weight
- 220 KB
- Volume
- 94
- Category
- Article
- ISSN
- 1591-951X
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This study was undertaken to assess a multiple-marker RT-PCR and Southern blot assay for detection of metastases in frozen sections of sentinel lymph nodes from breast cancer patients. Sentinel lymphadenectomy was performed in 41 AJCC (American Joint Committee on Cancer) stage I-IIIA breast cancer p
## BACKGROUND. Thirty percent of lymph node negative patients with operable breast carcinoma experience disease recurrence within 10 years. Retrospective serial sectioning of axillary lymph nodes has revealed undetected metastases in 9 -30% of these patients. These occult metastases have been show
## Abstract ## Background and Objectives To evaluate the efficacy of preoperative ultrasound (US) scanning in identifying lymph node metastasis before sentinel node biopsy (SNB), we conducted a prospective study on 125 patients with primary cutaneous melanoma (CM). ## Methods We prospectively en