✦ LIBER ✦

Sensory and motor evoked potentials in multiple system atrophy: A comparative study with Parkinson's disease

✍ Scribed by Prof. Giovanni Abbruzzese; Roberta Marchese; Carlo Trompetto

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 557 KB
Volume: 12
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870120309

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Somatosensory evoked potentials (SEPs) to median nerve stimulation and motor evoked potentials to transcranial magnetic stimulation (TMS) of the motor cortex were studied in 15 patients with multiple system atrophy (MSA) and compared with matched groups of 20 patients with idiopathic Parkinson's disease (PD) and of 20 normal controls (NCs). No SEP latency or amplitude abnormalities were observed, and, in particular, the frontal N30 component was not significantly depressed. No differences in TMS threshold for evoking responses in relaxed or active thenar muscles were observed. The mean central motor conduction time was normal for the biceps brachii and opponens pollicis muscles and prolonged in the MSA group for the tibilais anterior muscle. Recording SEPs is not useful to differentiate MSA from PD, while the presence of central motor conduction abnormalities may bring into question the diagnosis of idiopathic PD.

📜 SIMILAR VOLUMES

Do visual-evoked potentials and spatiote

Do visual-evoked potentials and spatiotemporal contrast sensitivity help to distinguish idiopathic Parkinson's disease and multiple system atrophy?

✍ I. Delalande; Jc. Hache; G. Forzy; M. Bughin; J. Benhadjali; A. Destée 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 572 KB

## Abstract A large number of patients with Parkinson's disease were reported to have abnormal visual‐evoked potentials (VEPs) and spatiotemporal contrast sensitivity (STCS) suggesting dopaminergic deficiency in the visual pathway, probably the retina. Until now, VEPs and STCS have not been studied

Presynaptic parkinsonism in multiple sys

Presynaptic parkinsonism in multiple system atrophy mimicking Parkinson's disease: A clinicopathological case study

✍ José Berciano; Francesc Valldeoriola; Isidre Ferrer; Jordi Rumià; Julio Pascual; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB

We describe the clinicopathological findings in a patient aged 63 years at death who, at age 55 years, developed levodopa-responsive parkinsonism with no atypical features. A diagnosis of idiopathic Parkinson's disease (PD) was made. During the clinical course, fluctuations and dyskinesias appeared.

Parkinsonism in multiple system atrophy:

Parkinsonism in multiple system atrophy: Natural history, severity (UPDRS-III), and disability assessment compared with Parkinson's disease

✍ François Tison; Farid Yekhlef; Virginie Chrysostome; Eric Balestre; Niall P. Qui 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB

We analyzed parkinsonian features in multiple system atrophy (MSA) compared with age- and disease duration-matched Parkinson's disease (PD) patients, and assessed the applicability of the Unified Parkinson's Disease Rating Scale (UPDRS) -III motor scale as a means of rating their severity. Cross-sec

Depression and self-reported depressive

Depression and self-reported depressive symptoms in multiple system atrophy compared to Parkinson's disease

✍ François Tison; Farid Yekhlef; Virginie Chrysostome 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 46 KB

Electromyography of the external anal sp

Electromyography of the external anal sphincter in patients with Parkinson's disease and multiple system atrophy: Frequency of abnormal spontaneous activity and polyphasic motor unit potentials

✍ Johannes Schwarz; Malte Kornhuber; Christian Bischoff; Andreas Straube 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 2 views

Electromyographic studies of the external anal sphincter muscle have received increasing attention in the differential diagnosis of patients with parkinsonism. Based on the fact that the external anal sphincter muscle is partly innervated by fibers that originate in Onuf's nucleus in the segments S2

Brain-derived neurotrophic factor gene p

Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy

✍ Masataka Nishimura; Sadako Kuno; Ryuji Kaji; Hideshi Kawakami 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 56 KB

## Abstract We studied two genetic polymorphisms (240C/T and 480G/A) of the brain‐derived neurotrophic factor (BDNF) gene in Japanese patients with Alzheimer's disease (AD, n = 172), Parkinson's disease (PD, n = 327), and multiple system atrophy (MSA, n = 122), as well as controls (n = 275). The di