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Sensor materials for the detection of human neutrophil elastase and cathepsin G activity in wound fluid

✍ Scribed by Andrea Hasmann; Ulrike Gewessler; Elisabeth Hulla; Konstantin P. Schneider; Barbara Binder; Antonio Francesko; Tzanko Tzanov; Michael Schintler; Job Van der Palen; Georg M. Guebitz; Eva Wehrschuetz-Sigl

Book ID
111244850
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
260 KB
Volume
20
Category
Article
ISSN
0906-6705

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✍ Peter Shamamian; Jess D. Schwartz; Ben J.Z. Pocock; Sara Monea; David Whiting; S πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 236 KB

## Abstract Gelatinase A (MMP‐2), a matrix metalloproteinase (MMP) involved in tumor invasion and angiogenesis, is secreted as an inactive zymogen (proMMP‐2) and activated by proteolytic cleavage. Here we report that polymorphonuclear neutrophil (PMN)‐derived elastase, cathepsin G, and proteinase‐3