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Effect of DNase on the activity of neutrophil elastase, cathepsin G and proteinase 3 in the presence of DNA

✍ Scribed by Jérôme Duranton; Didier Belorgey; Jacqueline Carrère; Lionel Donato; Thomas Moritz; Joseph G. Bieth


Book ID
117101812
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
95 KB
Volume
473
Category
Article
ISSN
0014-5793

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Activation of progelatinase A (MMP-2) by
✍ Peter Shamamian; Jess D. Schwartz; Ben J.Z. Pocock; Sara Monea; David Whiting; S 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 236 KB

## Abstract Gelatinase A (MMP‐2), a matrix metalloproteinase (MMP) involved in tumor invasion and angiogenesis, is secreted as an inactive zymogen (proMMP‐2) and activated by proteolytic cleavage. Here we report that polymorphonuclear neutrophil (PMN)‐derived elastase, cathepsin G, and proteinase‐3