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Sensitization of rotation behavior in rats with unilateral 6-hydroxydopamine or kainic acid-induced striatal lesions

✍ Scribed by Andrew B. Norman; Lindy M. Wyatt; Jeffrey P. Hildebrand; Mantana Kolmonpunporn; Carole A. Moody; Michael N. Lehman; Paul R. Sanberg

Book ID
113224159
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
459 KB
Volume
37
Category
Article
ISSN
0091-3057

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✍ Satoshi Goto; Kojiro Korematsu; Nobuhiro Inoue; Kazumichi Yamada; Taro Oyama; Sh πŸ“‚ Article πŸ“… 1993 πŸ› Springer-Verlag 🌐 English βš– 601 KB

The present study shows that systemic administration of the selective, non-competitive N-methyl-D-aspartate antagonist MK-801 [(+)-5-methyl-10,11-dihydroxy-5H-dibenzo (a,d)-cyclohepten-5,10-imine] dose-dependently induces ipsiversive rotational behavior in the rats with a unilateral striatal lesion