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Sensitization of human renal cell carcinoma cell lines to TRAIL-induced apoptosis by anthracyclines

โœ Scribed by XIU-XIAN WU; OSAMU OGAWA; YOSHIYUKI KAKEHI


Book ID
108976450
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
231 KB
Volume
11
Category
Article
ISSN
0919-8172

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## Abstract Aberrant PI3K/Akt signaling has been implicated in many human cancers, including prostate carcinomas. Currently different therapeutic strategies target the inhibition of this survival pathway. The nucleoside analog triciribine (TCN), which was initially described as a DNA synthesis inhi