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Sensitization of chronic lymphocytic leukemia cells to TRAIL-induced apoptosis by hyperthermia

✍ Scribed by Maryline Moulin; Charles Dumontet; André-Patrick Arrigo

Book ID: 116334318
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 600 KB
Volume: 250
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2006.10.019

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## Abstract B‐cell chronic lymphocytic leukaemia (B‐CLL) cells fail to undergo apoptosis. The mechanism underlying this resistance to cell death is still largely unknown. Tumour necrosis factor‐related apoptosis‐inducing ligand (TRAIL) effectively kills tumour cells but not normal cells, and thus r