Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL)
✍ Scribed by Nayoung Kim
- Book ID
- 107641880
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 264 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0253-6269
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## Abstract Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) induces apoptosis in a number of tumorogenic or transformed cells, yet is relatively non‐toxic to most normal cells, therefore, it is a promising agent for cancer therapy. However, some cancer cell lines were resistan
## Abstract Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) has been shown to induce apoptosis in numerous transformed cell lines but not in most normal cells. Although this selectivity offers a potential therapeutic application in cancer, not all cancers are sensitive to TRAIL‐medi