Sensitivity of Pyrimidines and Purines towards Neutron Irradiation
β Scribed by Prof. Dr. A. Wacker; P. Chandra
- Publisher
- John Wiley and Sons
- Year
- 1965
- Tongue
- English
- Weight
- 121 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0044-8249
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Before gas-liquid chromatographic (GLC) analysis of the purine and pyrimidine bases, nucleosides, or nucleotides can be accomplished, these compounds must be converted to suitable volatile derivatives. The trimethylsilylation of active hydrogens is overwhelmingly preferred for GLC with nucleic acid
The results of neutron irradiation of 36 patients with uterine sarcoma are presented. Patients were subdivided in 3 groups: A: no residual tumour post-surgery; B: macroscopic tumour ranging from <1 to 11 cm in diameter; C: advanced or metastatic disease. The median survival was 42 months (Group A),