𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Sensitivity of p53 Lysine Mutants to Ubiquitin-Directed Degradation Targeted by Human Papillomavirus E6

✍ Scribed by TIM CROOK; ROBERT L. LUDWIG; NICOLA J. MARSTON; DAGMAR WILLKOMM; KAREN H. VOUSDEN


Book ID
112270896
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
312 KB
Volume
217
Category
Article
ISSN
0042-6822

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Human papillomavirus type 16 E6 and HPV-
✍ Yongmin Liu; Ann McKalip; Brian Herman πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 583 KB

We and others have previously reported that human papillomavirus (HPV)-16 E6 protein expression sensitizes certain cell types to apoptosis. To confirm that this sensitization occurred in HPV's natural host cells, and to explore the mechanism(s) of sensitization, we infected human keratinocytes (HKCs

Targetting of the N-terminal domain of t
✍ Christine Giovane; Gilles TravΓ©; AmΓ©lie Briones; Yves Lutz; Bohdan Wasylyk; Etie πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 443 KB πŸ‘ 1 views

The E6 protein of cancer-associated human papillomavirus type 16 (HPV16) binds to cellular p53 and promotes its degradation through the ubiquitin pathway. In an attempt to identify the regions of E6 that could be targetted for functional inhibition, we generated monoclonal antibodies to the HPV16 E6