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Sensitivity of immunocompetent spleen cells of mice of different genotypes to alkylating agents

โœ Scribed by L. A. Pevnitskii; L. Yu. Telegin; Kim Nam Ir


Publisher
Springer US
Year
1985
Tongue
English
Weight
243 KB
Volume
100
Category
Article
ISSN
0007-4888

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Utilization ofin vivoalkylated metabolit
โœ M. I. Lerman; O. Yu. Abakumova; N. G. Kutcenko; I. S. Sokolova; L. B. Gorbacheva ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› Springer ๐ŸŒ English โš– 342 KB

In this paper it is shown that the cells of hepatoma 22a utilize alkylated metabolites, which are formed in vivo after a single injection of MNU. These antimetabolites are efficiently incorporated into tumor DNA, RNA and proteins. Abbreviations. MNU, N-methyl-N-nitroso-urea; TCA, trichloroacetic ac