Sensitivity and specificity of commercial ELISA kits for screening anti-LAV/HTLV III
✍ Scribed by Lutz G. Gürtler; Josef Eberle; Bernd Lorbeer; Friedrich Deinhardt
- Book ID
- 119114442
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 774 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0166-0934
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The sensitivity of nine commercial assays, Western blot, and a newly developed monoclonal antibody-based assay for antibody to human T lymphotropic virus type III/lymphoadenopathy associated virus (anti-HTLV III/LAV) were evaluated using a panel of mainly weak-positive sera. In tests on 20 sera thre
Serum specimens were tested for HIV antibodies by two commercially available ELISAs (Abbott HTLV I11 EIA and Du Pont HTLV III-ELISA). The specificity and sensitivity of these assays were determined by comparison with indirect immunofluorescence and Western blot analysis. Specificity ranged from 94.3