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Sensitive method for the determination of daunorubicin and all its known metabolites in plasma and heart by high-performance liquid chromatography with fluorescence detection

โœ Scribed by J. De Jong; P.A. Maessen; A. Akkerdaas; S.-F. Cheung; H.M. Pinedo; W.J.F. Van Der Vijgh

Book ID
108449671
Publisher
Elsevier Science
Year
1990
Weight
604 KB
Volume
529
Category
Article
ISSN
0378-4347

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A rapid sensitive and selective isocratic technique was developed for the analysis of plasma epirubicin and three of its known fluorescent metabolites epirubicinol, 4'-O-~-~-glucuronyl-4'-epidoxorubicin and 4'-O-fi-D-ghCUrOnyl 1,3-dihydro-4'-epidoxorubicin, with daunorubicin as an internal standard,