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Sensitive gas-liquid chromatographic method for determination of valproic acid in biological fluids

โœ Scribed by Chris J. Jensen; Roland Gugler


Book ID
108335026
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
372 KB
Volume
137
Category
Article
ISSN
1873-3778

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Gas chromatographic determination of val
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Valproic acid (di-n-propylacetic acid) is the free acid form of the drug'm-aketed under the names of Epilim, Sodium Valproate, and Depakine. Although valproic acid has been used for a number of years as an anti-epileptic drug, littIe has-been published on analytical methods and plasma levels I\*\*.

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A rapid gas-liquid chromatographic method far determining oxalic acid in biological materials' A number of gas cllromntographic (GC) methods for the analysis of the methyl ester of osalic acid in l~iological mntcrinls have hen reportedl-4. However, clifliculties in sample treatments : cg., isolatio