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Sensitive determination of 4-(4-chlorophenyl)-4-hydroxypiperidine, a metabolite of haloperidol, in a rat biological sample by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole

โœ Scribed by Yasuhiko Higashi; Shota Nakamura; Youichi Fujii


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
290 KB
Volume
20
Category
Article
ISSN
0269-3879

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A sensitive IIPLC analysis has been developed for the determination of anatoxin-a in cyanobacterial bloom material and in raw and treated waters. Efficient extraction of this toxin from its matrix can be achieved using solid-phase extraction with a weak cation exchanger. HPLC analysis with fluorimet