## Abstract In a study of 7498 American men of Japanese ancestry in Hawaii, 26 incident cases of leukemia or nonโHodgkin's lymphoma were identified after a followโup period of 19 years. Two of the cases, who were brothers, were diagnosed with adult Tโcell leukemia/lymphoma (ATL). Both of these brot
Sensitive detection and apoptotic cell death induction of adult T-cell leukemia/lymphoma (ATL) cells with photodynamic actions
โ Scribed by Oka, Takashi; Fujita, Hirofumi; Abd Al-Kader, Lamia; Murakami, Ichiro; Utsunomiya, Atae; Yoshino, Tadashi
- Book ID
- 121575601
- Publisher
- BioMed Central
- Year
- 2014
- Tongue
- English
- Weight
- 75 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1742-4690
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## Abstract Adult Tโcell leukemia/lymphoma (ATL) is a CD4^+^CD25^+^ Tโcell malignancy infected with human Tโcell leukemia virus typeโI (HTLVโI). HTLVโI infection causes the Tโcell dysfunction, which contributes to the immunodeficient state of the patients. Programmed deathโ1 (PDโ1) can negatively r
## Abstract Adenosine deaminase (ADA) was assayed in plasma from 14 patients with adult Tโcell leukemia (ATL) (eight with acute ATL and six with smoldering or chronic ATL), 20 male family members (ten were antiโATLA antibody positive and the other ten negative), and 25 normal individuals. ADA activ
The clinical characteristics of 33 patients with adult T-cell leukemia (ATL) are described. All patients were born and have lived in Miyazaki Prefecture (southwest of Japan). Because of a wide range of clinical presentations and courses, they were subdivided into 2 groups. In the high-risk group, pa