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Sensitive and selective detection of thrombin by using a cyclic peptide as affinity ligand

✍ Scribed by Zhao, Qiang; Gao, Jie

Book ID
125821000
Publisher
Elsevier Science
Year
2015
Tongue
English
Weight
529 KB
Volume
63
Category
Article
ISSN
0956-5663

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## Abstract To photomodulate the interaction of the phosphatidylinositol 3‐kinase SH3 domain with a peptide ligand, a cyclic peptide (__cyclic__‐1) with a photolabile side chain‐to‐side chain linker was synthesized. The conformation of __cyclic__‐1 differs from that of the parent linear peptide, bu