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Sensitive and selective bioanalytical assay for the determination of dobutamine in rat plasma samples

✍ Scribed by H. Lingeman; J. A. Haverhals; H. J. E. M. Reeuwijk; U. R. Tjaden; J. van der Greef

Book ID
112827078
Publisher
Springer
Year
1987
Tongue
English
Weight
461 KB
Volume
24
Category
Article
ISSN
0009-5893

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An assay suitable for hydroxyzine determination in human plasma following therapeutic doses was developed. The method involves GLC and chemical-ionization mass spectrometry of the acetate derivatives of hydroxyzine and of a pentadeuterated analog internal standard. Following administration of 100-mg