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Semisynthesis of Antitumoral Acetogenins: SAR of Functionalized Alkyl-Chain Bis-Tetrahydrofuranic Acetogenins, Specific Inhibitors of Mitochondrial Complex I

✍ Scribed by Gallardo, Teresa; Zafra-Polo, M. Carmen; Tormo, José R.; González, M. Carmen; Franck, Xavier; Estornell, Ernesto; Cortes, Diego


Book ID
127267060
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
95 KB
Volume
43
Category
Article
ISSN
0022-2623

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Tucupentol, a Novel Mono-tetrahydrofuran
✍ Olga Álvarez Colom; Adriana Neske; Nadia Chahboune; M. Carmen Zafra-Polo; Alicia 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB 👁 2 views

## Abstract magnified image Ten acetogenins, one of them new, were isolated from leaves and twigs of a Bolivian collection of __Annona montana.__ The new compound that we named tucupentol (**1**) is a mono‐tetrahydrofuran‐pentahydroxy‐acetogenin. The inhibitory potency of tucupentol (**1**) on the