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Semi-Synthesis of an O-Glycosylated docetaxel analogue

✍ Scribed by Anastasia Nikolakakis; Khadidja Haidara; Françoise Sauriol; Orval Mamer; Lolita O Zamir

Book ID
108479302
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
199 KB
Volume
11
Category
Article
ISSN
0968-0896

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✍ Wei-Shuo Fang; Qi-Cheng Fang; Xiao-Tian Liang 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 86 KB

The 2a-benzoylamido analogue of docetaxel 2 was synthesized with a double inversion of the C-2 configuration as the key step, and its cytotoxic activity towards three tumor cell lines was tested.