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Synthesis and Cytotoxicity of 2α-Amido Docetaxel Analogues.

✍ Scribed by Wei-Shuo Fang; Ying Liu; Hong-Yan Liu; Shao-Feng Xu; Liang Wang; Qi-Cheng Fang

Book ID
101937702
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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Synthesis of the 2α-benzoylamido analogue of docetaxel
✍ Wei-Shuo Fang; Qi-Cheng Fang; Xiao-Tian Liang 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 86 KB

The 2a-benzoylamido analogue of docetaxel 2 was synthesized with a double inversion of the C-2 configuration as the key step, and its cytotoxic activity towards three tumor cell lines was tested.