CD4+CD25+ T cells as immunoregulatory T
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Jian-Guo Chai; JuliaβY.βS. Tsang; Robert Lechler; Elizabeth Simpson; Julian Dyso
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Article
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2002
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John Wiley and Sons
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English
β 482 KB
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We have further characterized the in vitro phenotype and function of anergic and suppressive CD4(+)25(+) T cells. Following TCR ligation, DO.11.10 CD4(+)25(+) T cells suppress the activation of OT-1 CD8(+)25(-) T cells in an antigen nonspecific manner. Although suppression was seen when using a mixt