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Selfassociation of daunomycin

✍ Scribed by Chaires, Jonathan B.; Dattagupta, Nanibhushan; Crothers, Donald M.

Book ID: 120886686
Publisher: American Chemical Society
Year: 1982
Tongue: English
Weight: 644 KB
Volume: 21
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi00260a004

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Daunomycin (l), .6, a bacterial metabolite, has shown interesting biological activity, especially as an antitumor agent. Mild acidic hydrolysis of daunomycin yields an aglycone, daunomycinone, 1, and the amino sugar daunosamine (2), 2. The structure of the sugar has been elucidated (2) and was confi