Self-assembling peptides as a drug carrier
β Scribed by Xiaojun Zhao
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 53 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1549-9634
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## Abstract The selfβassembling behavior, at physiological pH, of the amphiphile peptide (C18)~2~L5CCK8 in nanostructures is reported. Stable aggregates presenting a critical micellar concentration of 2 Γ 10^β6^ mol kg^β1^, and characterized by water exposed CCK8 peptide in Ξ²βsheet conformation, ar
## Abstract The selfβassembly of peptides is explored as an alternative route towards the development of new injectable joint lubricants for osteoarthritis (OA). The versatility of the peptide chemistry allows the incorporation of behavior reminiscent of hyaluronic acid (HA), while the triggered __