Selenium dioxide E-methyl oxidation of suitably protected geranyl derivatives—synthesis of farnesyl mimics

✍ Scribed by Ian J.S Fairlamb; Julia M Dickinson; Mathew Pegg

• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 89 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)00110-1

✦ Synopsis

Difunctional allylic terpenes are important synthetic building blocks. Functionalisation of protected geranyl derivatives by SeO 2 provides a convenient route to such compounds. The effect of the geranyl protecting group on the oxidation of the terminal E-methyl group was systematically investigated.