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Selenium and cancer risk in CHEK2 mutation carriers

✍ Scribed by Satish Gupta; Katarzyna Jaworska; Katarzyna Durda; Grzegorz Sukiennicki; Magdalena Muszyńska; Anna Jakubowska; Jan Lubinski


Book ID
115027867
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
63 KB
Volume
10
Category
Article
ISSN
1897-4287

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CHEK2 mutations and HNPCC-related colore
✍ Janina Suchy; Cezary Cybulski; Dominika Wokołorczyk; Oleg Oszurek; Bohdan Górski 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 128 KB

## Abstract Recently, the 1100delC variant of cell cycle checkpoint kinase 2 (CHEK2) has been reported to confer a colorectal cancer risk in hereditary non‐polyposis‐colorectal cancer (HNPCC) and HNPCC‐related families in the Netherlands. To investigate whether CHEK2 mutations confer increased canc