Selectivity difference between carboxyethyl-β-cyclodextrin and carboxymethyl-β-cyclodextrin in enantioseparations of drugs by capillary electrophoresis
✍ Scribed by Xueqin Ren; Xiaodan Su; Aijin Huang; Yiliang Sun; Zengpei Sun
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 313 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0009-5893
No coin nor oath required. For personal study only.
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## Abstract According to the model of Wren and Rowe, the separation between two enantiomers in capillary electrophoresis (CE) decreases if an organic modifier is added to the run buffer containing a neutral cyclodextrin (CD) in a concentration below its optimal value in a solvent‐free system. In pr
## Enantioseparation of dihydropyridine derivatives by means of neutral and negatively charged b-cyclodextrin derivatives using capillary electrophoresis Employing capillary electrophoresis, the racemates of 29 acidic, neutral and basic dihydropyridines (DHPs) were separated by means of neutral an
-cyclodextrin (CD) and its derivatives HP--CD, DM--CD, and TM--CD have been employed as chiral selectors for the separation of three nonsteroidal antiinflammatory drugs (NSAIDs) and anticoagulant at relatively low concentration (8-15 mM) by capillary zone electrophoresis (CZE). In this study, ba