𝔖 Bobbio Scriptorium
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Selectively deuterated amino acid analogues synthesis, Incorporation into proteins and NMR properties

✍ Scribed by Matthews, H.Randall; Matthews, Kathleen S.; Opella, Stanley J.


Book ID
122873794
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
828 KB
Volume
497
Category
Article
ISSN
0304-4165

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For the application of multidimensional NMR spectroscopy to larger proteins, it would be useful to perform selective labeling of one of the 20 amino acids. For some amino acids, however, amino acid metabolism drastically reduces the efficiency and selectivity of labeling in in vivo expression system