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Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis

✍ Scribed by Susanne A Snoek; Marleen I Verstege; Esmerij P van der Zanden; Nigel Deeks; David C Bulmer; Michael Skynner; Kevin Lee; Anje A te Velde; Guy E Boeckxstaens; Wouter J de Jonge

Book ID
111219587
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
679 KB
Volume
160
Category
Article
ISSN
0007-1188

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## Abstract Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) are common forms of dementia in the elderly associated with cholinergic dysfunction, including reductions in nicotinic acetylcholine receptors (nAChRs). In AD, astrocytes are implicated in the formation of senile plaques, one