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Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection

✍ Scribed by Raquelli Ganel; Tony Ho; Nicholas J. Maragakis; Mandy Jackson; Joseph P. Steiner; Jeffrey D. Rothstein


Book ID
113811913
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
519 KB
Volume
21
Category
Article
ISSN
0969-9961

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✍ M.I. GonzΓ‘lez; A. Ortega πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 96 KB

The effects of phorbol 12-tetradecanoyl-13-acetate (TPA) and dibutyryl cAMP on the glutamate transport present in chick Bergmann glial cell (BGC) cultures were examined. TPA produced a significant decrease in [ 3 H]-D-aspartate uptake, while dibutyryl cAMP treatment elicited a slight reduction in th