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Selective transformations of penicillins and cephalosporins with pen G acylase

✍ Scribed by Claudio Fuganti; Romina Rigoni; Stefano Servi

Publisher
Springer Netherlands
Year
1994
Tongue
English
Weight
219 KB
Volume
16
Category
Article
ISSN
0141-5492

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✦ Synopsis

Immobilised Penicillin G acylase from E. coli hydrolyses penicillin and cephalosporin derivatives protected at the carboxy group as the phenylacetoxymethylene esters. The corresponding hydrolysis of penicillin V retains the phenoxyacetyl moiety. Kinetic data of the hydrolysis are reported.

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