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Selective sweeps for recessive alleles and for other modes of dominance

✍ Scribed by G. Ewing; J. Hermisson; P. Pfaffelhuber; J. Rudolf

Publisher
Springer
Year
2010
Tongue
English
Weight
684 KB
Volume
63
Category
Article
ISSN
0303-6812

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Mutations for the autosomal recessive and autosomal dominant forms of polycystic kidney disease are not allelic
✍ MichΓ¨le Ramsay; Stephen T. Reeders; Peter D. Thomson; Lawrence S. Milner; L. Laz πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 278 KB

The autosomal dominant form of polycystic kidney disease (ADPKD) has been linked to the alpha-globin gene locus on 16p. Linkage studies between the autosomal recessive type (ARPKD) and the 3' HVR of the alpha-globin gene cluster showed that the ARPKD and ADPKD are not allelic.